CASE CLOSED … what really happened in the 2001 anthrax attacks?

* The AR Management System system relating to Protocols confirms Dr. Ivins’ challenges (and the other challenges using virulent Ames from RMR 1029) were done under Biolevel-3 conditions.

Posted by Lew Weinstein on December 24, 2011

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3 Responses to “* The AR Management System system relating to Protocols confirms Dr. Ivins’ challenges (and the other challenges using virulent Ames from RMR 1029) were done under Biolevel-3 conditions.”

  1. DXer said

    There is a new category, new as of today I believe, at the reading room titled “Protocols.” Presently, there is the list of protocols. I presume various protocols, to the extent requested and produced, will be uploaded there.

    https://mrmc-www.army.mil/content/foia_reading_room/Protocols/List.pdf

    There are important ones that I did not include in the earlier selection of title cards posted above (due to space constraints).

    See
    Anthrax vaccine efficacy in golden Syrian hamsters.
    Fellows PF, Linscott MK, Little SF, Gibbs P, Ivins BE.
    Vaccine. 2002 Jan 31;20(9-10):1421-4.

    See also

    Efficacy of a human anthrax vaccine in guinea pigs, rabbits, and rhesus macaques against challenge by Bacillus anthracis isolates of diverse geographical origin.
    Fellows PF, Linscott MK, Ivins BE, Pitt ML, Rossi CA, Gibbs PH, Friedlander AM.
    Vaccine. 2001 Apr 30;19(23-24):3241-7. Erratum in: Vaccine 2001 Nov 12;20(3-4):635.

  2. DXer said

    Let’s consider the example of a later protocol on which Dr. Ivins was a co-investigator — not one of the ones represented above.

    One is titled “Immunization of Rabbits with a Recombinant Protective Antigen (rPA) Vaccine Against Aerosol Challenge by Spores of Virulent Bacillus anthraces.”

    Even in this later protocol involving an aerosol challenges conducted in Building 1412 — as distinguished from the subcutaneous challenges conducted in 1425 in Sep/Oct 2001 — the rabbits were kept in Building 1425, Suite B3 before and after the aerosol challenge in 1412.

    Monitoring continued for 21 days after though, as I recall (without rechecking the protocol), most unvaccinated rabbits would die 2-4 days and if any vaccinated animals died, they typically would die within 4-8 days.

    • DXer said

      Let’s consider another later protocol involving Dr. Ivins — again long after the Sep-Oct 2001 period. The protocol is “Immunology and Efficacy of Recombinant Protein Vaccines and Novel Mucosal Adjuvants Delivered By Inhalation in Guinea Pigs.”

      Given that it was an aerosol experiment, it was conducted in Building 1412, not 1425.

      The animals in that Ivins study were housed in 1412.

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